The Science of the Microbiome: One Conversation at a Time
Each episode explores the microbiome from a different angle: basic research, clinical applications, guest scientists, and borderline cases. Designed for those who want to look beyond the headlines.
The brain and the gut are in constant communication. Dr. Biazzo’s research explores how changes in the microbiota contribute to neurodegenerative diseases, behavioral disorders, and infections such as Clostridium difficile.
The microbiota cannot be seen with the naked eye—it must be sequenced. Dr. Biazzo compared Nanopore and Illumina sequencing technologies to establish the optimal standard for the taxonomic classification of the microbiota at the species level.
The skin has its own bacterial ecosystem. The S-MBRT project and the SkinDuo™ formulation demonstrate how topical probiotics based on Lactobacillus plantarum can reduce acne by acting on the skin microbiome without the use of drugs.
The immune system’s response to cancer treatments also depends on the composition of the microbiome. The PIRIOP project is investigating how an individual’s microbial profile can predict—and optimize—the response to immunotherapy.
VagiBiome-AI combines metagenomics and AI predictive models to analyze the gut and vaginal microbiomes in tandem—opening up new possibilities for hormonal health, fertility, and the prevention of recurrent infections.
The DPHAGE project is studying the microbiome in individuals aged 50 to 80 to identify biomarkers of silent chronic inflammation—the “smoldering fire” that accelerates aging. The findings align with field research conducted in Japan.
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